In a post-credits scene, Logan is seen inside a caged pit in the jungle, presumably going through the same torture methods as Rorke. Eurogamer was less critical of the campaign, commenting that "the Ghosts campaign can't help but feel like a step backwards", but that "it's still capable of being devilishly entertaining" and "moment-to-moment thrills are still there, if muted by expectation". However, one of the doctors working at Nightfall, Samantha Cross, began to fall under the Ancestors' influence, and slowly became one of their hypnotic spies, capable of telepathic abilities. The map takes place in a launch facility, 3 months after "Awakening", where the players are pit in a final battle against the forces of the Cryptids.

The player takes on the role of an elite unnamed soldier, whose appearance is carried from the player's multiplayer character. Ghosts inherits much of the core gameplay and structure of previous titles, with a mission-based campaign and an open-ended multiplayer, but introduces a near-future setting to the series as well as an increased focus on tactical gameplay, including the addition of new "Squads" modes and orbital strike superweapons to the multiplayer. The new Extinction mode is particularly good, but it's the highlight in a title that's following a tired recipe. Archer and his men later arrived at the island where the Ark is located, however they encounter hordes of Cryptids, leading to Archer's hand being infected.Crates are dropped in random locations throughout the match that contains more weapons and ammo for the players to compete for. The player can get the ODIN kill streak by either getting a certain amount of kills or by killing the top player on the other team and then completing various challenges after picking up a blue briefcase that is dropped.

Ground War: Containing a rotating playlist with Domination and Team Deathmatch, but with 12–18 players and a 100-kill limit for TDM. During a mission into No Man's Land, they spot Federation agent Gabriel Rorke interrogating Ghost member Ajax. Hesh and Logan are part of an Army special unit under the command of Elias and are accompanied by Riley, their loyal military-trained German Shepherd. The third map, "Mayday", is released as part of the Devastation DLC pack, and is the second of four episodes of Extinction. The second map, "Nightfall", is released as part of the Onslaught DLC pack, and is advertised as the first of the four episodic contents for Extinction.

The music video for the song features various footage from the game's single player campaign, and other elements from the game. Additionally, it includes the next installment in the Extinction episodic contents, titled "Mayday". Extinction is a 4-player co-op mode, which pits the player(s) against various types of aliens (known altogether as Cryptids) in a base-defending survival style map. Every five seconds a flag in controlled will gain a player's team a point, if a player's team controls two or three flags, they gain two or three points.