Assassin's Creed received multiple nominations at AIAS' 11th Annual Interactive Achievement Awards: " Adventure Game of the Year", "Outstanding Innovation in Gaming" and outstanding achievement in " Animation" (which it won), " Art Direction", " Gameplay Engineering" and " Visual Engineering". Ubisoft was apprehensive to a Prince of Persia game without the Prince as the playable character, but this led the marketing division to suggest the name Assassin's Creed, playing off the creed of the Assassins, "nothing is true; everything is permitted". Originally Revelations was announced as Assassin's Creed: Lost Legacy, and conceptualized as a Nintendo 3DS title focusing on Ezio traveling to Masyaf to explore Altaïr's legacy and uncover the origins of the Assassin Brotherhood. Abstergo has kidnapped people who are descendants of past Assassins to locate the missing Pieces of Eden via the Animus. Players choose between two playable protagonists, Alexios and Kassandra, and embark on a quest to discover mysteries surrounding their family, as well as to undermine a proto-Templar organization: the Cult of Kosmos.

From Assassin's Creed IV: Black Flag to Assassin's Creed Syndicate, Assassin initiates and employees of Abstergo (a company used as a front by the modern-day Templars) record genetic memories using the Helix software, helping the Templars and Assassins find new Pieces of Eden in the modern world. Once the area is at high alert, crowds run and scatter while guards attempt to chase and bring down Altaïr; to reduce the alert level, the player must control Altaïr as to break the guards' line of sight and then find a hiding space, such as a haystack or rooftop garden, or blend in with the citizens sitting on benches or wandering scholars. At the PlayStation Showcase event in May 2023, a new trailer for the game was shown, which revealed the release date to be October 12; [57] however, it was later changed to October 5. Eurogamer stated that the gameplay "never evolves and ultimately becomes a bit boring, and quite amazingly repetitive.The main story is set during the Peloponnesian War between Athens and Sparta, at the height of Classical Greece. In December 2014, images and information leaked for a new Assassin's Creed game, titled or code-named Victory, which was later confirmed by Ubisoft.

Some long-standing features of the series were eliminated for this purpose, such as the social stealth mechanic.The prince character was dropped, and the game focused solely on the assassin as the playable character. When the synchronization bar is full, the player has the additional option to use the Eagle Vision, which allows the computer-rendered memory to highlight all visible characters in colours corresponding to whether they are allies (blue), foes (red), neutral (white), or the target of their assassination (gold). Desmond is used by Abstergo to find Pieces of Eden but is freed by Lucy Stillman, an undercover agent for the Assassins. The game offers a large wilderness area in the form of the Frontier and the Davenport Homestead, where the player can hunt animals for materials, which subsequently can be used to construct goods to be traded and sold throughout the colonies.

In Constantinople, Ezio becomes caught in a war of succession between Sultan Bayezid II's sons, Selim and Ahmet, and must confront a conspiracy masterminded by the Byzantine Templars, who are taking advantage of the chaos to try and reclaim the city, as well as acquire the keys to Altaïr's library themselves. Altaïr's story begins with his demotion to the rank of Novice Assassin after he botches an attempt by the Assassins to recover a Piece of Eden, the Apple of Eden, from the Templars. All that remained of the Isu were the traces of their memories in the world's mythologies, and religions, while the Pieces of Eden were lost to time. In the present-day, the player character is a player of Helix, an Animus-powered gaming device produced by Abstergo, who hope to use their unaware player base to locate more Pieces of Eden. An original Assassin's Creed title for the PlayStation Vita was announced to be in development during Gamescom 2011 and would feature a new story with new characters; on June 4, 2012, at E3, Liberation was officially announced.The entire game is presented as a product developed by the in-universe company Abstergo Entertainment, who have done a heavy amount of censoring in regards to the Assassin–Templar conflict.

As Microsoft and Sony had not yet revealed their next consoles, the game's initial development from January 2004 was aimed as a PlayStation 2 title, following the same linear approach that The Sands of Time had taken. This also helped them to give the feeling to the player that they had as much freedom as possible within the game, a concept that had originated from the success of the Grand Theft Auto series.At various points during their playthrough, the player is contacted by the hacking collective Erudito, who helps them uncensor the game to learn the true nature of the events depicted. Being originally released as DLC for Black Flag, Freedom Cry's gameplay is virtually identical, though it does feature several new additions. The Ubisoft Montreal team decided to take the gameplay from The Sands of Time into an open-world approach, taking advantage of the improved processing power to render larger spaces and crowds. Assassin's Creed Unity was released concurrently with Rogue in November 2014 for the PlayStation 4, Xbox One, Windows, and Google Stadia.