Children between the age of 12 to 18 can also use this medicine. Children below the age of 12 must consult with a doctor, and only if they permit can they start the consumption. If you are concerned about addiction to 'over the counter' medication, we urge you to visit the below links for professional help and advice: Nurofen Meltlets is a non-selective inhibitor of cyclooxygenase, an enzyme invovled in prostaglandin synthesis via the arachidonic acid pathway. Its pharmacological effects are believed to be due to inhibition cylooxygenase-2 (COX-2) which decreases the synthesis of prostaglandins involved in mediating inflammation, pain, fever and swelling. Antipyretic effects may be due to action on the hypothalamus, resulting in an increased peripheral blood flow, vasodilation, and subsequent heat dissipation. Inhibition of COX-1 is thought to cause some of the side effects of ibuprofen including GI ulceration. Nurofen Meltlets is administered as a racemic mixture. The R-enantiomer undergoes extensive interconversion to the S-enantiomerin vivo. The S-enantiomer is believed to be the more pharmacologically active enantiomer. In children ingestion of more than 400 mg/kg may cause symptoms. In adults the dose response effect is less clear cut. The half-life in overdose is 1.5-3 hours.

Chronic hepatic necrosis has been reported in a patient who took daily therapeutic doses of paracetamol for about a year and liver damage has been reported after daily ingestion of excessive amounts for shorter periods. A review of a group of patients with chronic active hepatitis failed to reveal differences in the abnormalities of liver function in those who were long-term users of paracetamol nor was the control of their disease improved after paracetamol withdrawal. The speed of absorption of paracetamol may be increased by metoclopramide or domperidone and absorption reduced by cholestyramine. Anti-platelet agents and selective serotonin reuptake inhibitors (SSRIs): Increased risk of gastrointestinal bleeding (see section 4.4).

What are Nurofen Meltlets?

Yes, Nurofen has been discontinued in many parts of the world, such as Ireland, Australia, and the United States of America. This was done because this medicine was accused of a lot of controversial films, such as causing skin-related issues and not being effective.

If this product is required for children and adolescents for more than 2 days or if symptoms worsen, seek advice from your GP cardiopulmonary toxicity (premature constriction/closure of the ductus arteriosus and pulmonary hypertension); The antipyretic effect is reported to be linked to the effect on the prostanoid synthesis due to the fact that the prostanoids are the main signaling mediator of pyresis in the hypothalamic-preoptic region. Do not give this medicine to your child for more than 3 days without speaking to your doctor or pharmacist

Prescriptions must be written on an Authority Prescription Form, and the approval number must be noted on the prescription. Pharmacists cannot dispense the item as a pharmaceutical benefit unless it has been approved by Medicare Australia (indicated by the presence of the approval number). Acute renal failure, papillary necrosis, especially in long-term use, associated with increased serum urea and oedema.

You should start to notice the pain relieving effects of Nurofen Meltlets within 30 to 60 minutes of taking the tablets. Do NOT take this product if you are allergic to any of the ingredients (see ingredients tab for full list) or if you: This medicine contains 0.00064mg benzyl alcohol in each tablet. Benzyl alcohol may cause allergic reactions. Ask your doctor or pharmacist for advice if you are pregnant or breastfeeding, or if you have a liver or kidney disease. This is because large amounts of benzyl alcohol can build-up in your body and may cause side effects (called "metabolic acidosis")."

At The Independent Pharmacy we strive to provide a service that is accessible and entirely focused towards our customers. We therefore provide a choice of multiple delivery options, including next day delivery, that are designed to work around you. This is why this medicine brand came under the government’s radar, which decided to discontinue its sale in the market. The Britain government announced that the medicine would be taken off the shelves and would no longer be sold in the market.