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How to Starve Cancer

How to Starve Cancer

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For a long time, the prevailing thought was that altered metabolism in cancer cells was the result of genes and mutations that determined metabolism,” says Jason Locasale, a cancer biologist at Duke University. “Now, as we know, it’s a complex interaction of environment and genes, and one of the major factors at play is nutrition.” Galima bandyti argumentuoti, kad čia tik vienas atvejis, kad nežinia dėl ko pavyko pasveikti, kad už pasveikimą atsakinga chemoterapija, o ne tie magiški vaistai. Visi šie punktai turi pagrindą. Tačiau lieka dar vienas didelis BET. Jane yra tokia gan konkreti ir ne iš kelmo spirta moteriškė, ir visą savo gydymo eigą, visus vaistus ir papildus ji kruopščiai research'ino. To rezultatas yra daugiau nei 250 nuorodų į atliktus tyrimus, ir rašydamas "tyrimus", aš turiu omeny tuos "tikrus" tyrimus, peer reviewed and published stiliaus tyrimus, kuriuos visus kiekvienas norintis gali susirasti tokiuose kuklučiuose saituose kaip NCBI, PubMed, International Journal of Oncology ir taip toliau.

Now, 18 years later, after suffering from cervical cancer, secondary lung cancer, and treatment-related myelodysplasia, she is alive, well, and cancer-free. Unfortunately, just a few months later, Jane started coughing up blood, and found out that her worst nightmare had come true: Her cervical cancer had spread to her lungs. One fan even asked for more updates regarding his lifestyle change and wrote: "Ooh could you post more of your meal pics? Very interested on how this works and what you eat, amazing. Keep on keeping on". The importance of nutrition has long been accepted for conditions such as diabetes and hypertension, diagnoses that come with well-known dietary prescriptions. Even the most commonly used drug in type 2 diabetes, metformin, has been found in clinical trials to be inferior to diet and exercise. Cell biologists like Locasale see extending that line of thinking to cancer as a logical step, because at the cellular level, cancer is also a disease of metabolic pathways. Because cancer is a term that encapsulates many different diseases—with different changes in different metabolic pathways in different cells in different parts of the body—no single metabolic therapy is right for every person. What makes one cancer grow more slowly could conceivably hasten another. Just as avoiding excessive sugar is crucial for people with diabetes, lest they lose their vision and feet, sugar can save the life of a person with critical hypoglycemia.But McLelland refused to go down without a fight. Taking matters into her own hands, she dug through medical journals, poring over long-forgotten research and overlooked evidence, looking for clues to overcoming her cancer. And a breast cancer patient who was told by her oncologist she was going to die is still alive and well, going to the gym, working as a nurse, and living a full life—all as a result of following McLelland’s approach to starving her cancer. After intensive research, McLelland concluded that all of these drugs would starve the cancer from different angles: dipyridamole cut off cancer’s access to protein, metformin cut off access to glucose, and the statin cut off access to fat. Once the cancer cells were in their weakened state, the addition of etodolac could help finish them off. McLelland had repeatedly been told that diet had no impact on cancer, but the fact that her lung tumor had remained the size of a golf ball—and the fact that there were no tumors in other locations in her body—proved to her that the dietary changes she had already made were making a difference.

Cancer doesn’t die when you halt its primary fuel supply,” Van Tine said. “Instead, it turns on all these salvage pathways. In this paper, we identified the salvage pathways. Then we showed that when you drug them, too, you kill cells. Our study showed that tumors actually shrink under these conditions. This is the first time tumors have been shown to shrink using just metabolism drugs and no other anti-cancer strategies.”The first big gun was a cardiovascular drug called dipyridamole, which stops protein from getting into the cancer cell, a key factor in starving leukemia, according to McLelland.

This work was supported by grants from CJ’s Journey; The Sarcoma Foundation of America; a Sarcoma Alliance for Research and Collaboration Career Development Award; and Polaris Pharmaceuticals. Polaris Pharmaceuticals provided funding and the arginine-depleting drug, ADI-PEG20 (pegylated arginine deiminase). For now, unless an oncologist has advised a specific diet tailored to your specific tumor, the most common recommendation is to eat a generally healthy diet. None of this challenges the principle that staying well nourished is part of a healthy approach to any disease; and there is no evidence that overall starvation is good or even safe. But focusing on specific patterns of eating will likely be part of many cancer-treatment guidelines in coming years.You could see that my approach had slowed the tumor’s growth,” said McLelland. “I may have had that tumor for a long time. That was actually quite reassuring for me.”

If you have any questions on the scientific content of this article, please call a Life Extension ® Wellness Specialist at 1-866-864-3027. Her diet and numerous supplements were already helping on that front—particularly berberine, hydroxycitrate, gymnema, curcumin, niacin, and pycnogenol—all of which were inhibiting key pathways that are abnormal in cancer. She also underwent treatment with high-dose intravenous vitamin C. What made the diagnosis even more tragic was the fact that McLelland’s doctor had misdiagnosed her for years. Since cervical cancer is highly treatable in its early stages, her tragedy could have been avoided.

Jane McLelland’s Key Cancer-Starving Supplements:

Keep it up stay strong & enjoy your amazing family,” wrote one. Meanwhile another added: “Keeping up that awesome spirit Jonnie! Thank u for sharing your journey and inspiring others!”



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